High contiguity genome sequence of a multidrug-resistant hospital isolate of Enterobacter hormaechei.

ABSTRACT:

Background

Enterobacter hormaechei is an important emerging pathogen and a key member of the highly diverse Enterobacter cloacae complex. E. hormaechei strains can persist and spread in nosocomial environments, and often exhibit resistance to multiple clinically important antibiotics. However, the genomic regions that harbour resistance determinants are typically highly repetitive and impossible to resolve with standard short-read sequencing technologies.

Results

Here we used both short- and long-read methods to sequence the genome of a multidrug-resistant hospital isolate (C15117), which we identified as E. hormaechei. Hybrid assembly generated a complete circular chromosome of 4,739,272 bp and a fully resolved plasmid of 339,920 bp containing se

SUBMITTER: Monahan LG 

PROVIDER: S-EPMC6373042 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature