Testing a biobehavioral model of fatigue before adjuvant therapy in women with breast cancer.

ABSTRACT: BACKGROUND:Fatigue is one of the most common and disabling side effects of cancer and its treatment. Although research typically has focused on fatigue that occurs during and after treatment, patients may experience fatigue even before treatment onset. The current study was designed to identify biobehavioral risk factors associated with fatigue before adjuvant therapy in women with early-stage breast cancer. METHODS:Patients with stage 0 to stage IIIA breast cancer (270 women) were recruited before the onset of adjuvant or neoadjuvant therapy with radiotherapy, chemotherapy, and/or endocrine therapy. Host factors that may influence fatigue were identified from an empirically based, biobehavioral model and assessed using self-report questionnaires, medical record review, and blood collectio

SUBMITTER: Bower JE 

PROVIDER: S-EPMC6373488 | biostudies-literature | 2019 Feb

REPOSITORIES: biostudies-literature