Effect of Lung Volume Reduction Surgery on Respiratory Muscle Strength in Advanced Emphysema.

ABSTRACT: Background: Long-term effects of lung volume reduction surgery (LVRS) on respiratory muscle strength and effects of age, sex, and emphysema pattern on these changes are unknown. Therefore, we aimed to determine the long-term effect of LVRS on respiratory muscle strength changes in severe emphysema. Methods: The National Emphysema Treatment Trial was a prospective controlled multicentered trial, comparing LVRS to optimal medical treatment on survival and maximal exercise capacity. We examined percentage change in maximum inspiratory pressure (MIP) from baseline to 36 months follow-up to determine impact of LVRS as well as age, sex, emphysema pattern and exercise capacity on changes in MIP compared to medical treatment. Results: LVRS individuals had significantly greater

SUBMITTER: Criner RN 

PROVIDER: S-EPMC6373585 | biostudies-literature | 2018 Oct

REPOSITORIES: biostudies-literature