Resting-state connectivity within and across neural circuits in anorexia nervosa.

ABSTRACT:

Introduction

Obsessional thoughts and ritualized eating behaviors are characteristic of Anorexia Nervosa (AN), leading to the common suggestion that the illness shares neurobiology with obsessive-compulsive disorder (OCD). Resting-state functional connectivity MRI (rs-fcMRI) is a measure of functional neural architecture. This longitudinal study examined functional connectivity in AN within the limbic cortico-striato-thalamo-cortical (CSTC) loop, as well as in the salience network, the default mode network, and the executive control network (components of the triple network model of psychopathology).

Methods

Resting-state functional connectivity MRI scans were collected in unmedicated female inpatients with AN (n = 25) and healthy controls (HC; n = 24). Individuals with AN w

SUBMITTER: Uniacke B 

PROVIDER: S-EPMC6373651 | biostudies-literature | 2019 Jan

REPOSITORIES: biostudies-literature