Dataset Information

Effect of intensivist involvement on clinical outcomes in patients with advanced lung cancer admitted to the intensive care unit.

ABSTRACT:

Purpose

Intensive care unit (ICU)-related mortality for lung cancer is ranked highest among the solid tumors and little information exists on the role of intensivists on clinical outcomes. This study aimed to elucidate the intensivist's contribution toward clinical outcomes.

Materials and methods

Data of advanced lung cancer patients, including stage IIIB or IV non-small cell lung cancer and extensive-stage small cell lung cancer, admitted to the ICU from 2005 to 2016 were analyzed. Multivariate logistic regression was performed to determine variables associated with ICU and in-hospital mortality. Autoregressive integrated moving average (ARIMA) for time-series was used to assess the intensivist's impact.

Results

Of 264 patients, 85 (32.2%) were admitted to the ICU before and 179 (67.8%) after organized intensive care introduction in 2011. Before and after 2011, the changes observed were as follows: ICU mortality rate, 43.5% to 40.2%, respectively (p = 0.610); hospital mortality rate, 82.4% to 65. 9% (p = 0.006). The duration of ICU and hospital stay decreased after 2011 (14.5±16.5 vs. 8.3 ± 8.6, p < 0.001; 36.6 ± 37.2 vs. 22.0 ± 19.6, p < 0.001). On multivariate analysis, admission after 2011 was independently associated with decreased hospital mortality (Odds ratio 0.42, 95% confidence interval 0.21-0.77, p = 0.006). In ARIMA models, intensivist involvement was associated with significantly reduced hospital mortality. (Estimate -17.95, standard error 5.31, p = 0.001).

Conclusion

In patients with advanced lung cancer, organized intensive care could contribute to improved clinical outcomes.

SUBMITTER: Song JH

PROVIDER: S-EPMC6373899 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature

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Publications

Effect of intensivist involvement on clinical outcomes in patients with advanced lung cancer admitted to the intensive care unit.

Song Jin Hwa JH Kim Sooyeon S Lee Hyun Woo HW Lee Yeon Joo YJ Kim Mi-Jung MJ Park Jong Sun JS Kim Yu Jung YJ Yoon Ho Il HI Lee Jae Ho JH Lee Jong Seok JS Lee Choon-Taek CT Cho Young-Jae YJ

PloS one 20190213 2

<h4>Purpose</h4>Intensive care unit (ICU)-related mortality for lung cancer is ranked highest among the solid tumors and little information exists on the role of intensivists on clinical outcomes. This study aimed to elucidate the intensivist's contribution toward clinical outcomes.<h4>Materials and methods</h4>Data of advanced lung cancer patients, including stage IIIB or IV non-small cell lung cancer and extensive-stage small cell lung cancer, admitted to the ICU from 2005 to 2016 were analyze ...[more]

PMID: 30759088

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Dataset Information

Effect of intensivist involvement on clinical outcomes in patients with advanced lung cancer admitted to the intensive care unit.

Purpose

Materials and methods

Results

Conclusion

Publications

Effect of intensivist involvement on clinical outcomes in patients with advanced lung cancer admitted to the intensive care unit.

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