FMRI Stroop and behavioral treatment for cocaine-dependence: Preliminary findings in methadone-maintained individuals.

ABSTRACT:

Background

Although behavioral treatment for cocaine use disorders is common, the use of cognitive neuroscience methods to investigate these treatments' mechanisms of action remains limited. Cognitive control (e.g., as measured by the Stroop task) has been proposed to be central to cocaine-use disorders, including treatment response.

Methods

Participants were methadone-maintained, cocaine-dependent individuals who were participating in a randomized clinical trial (RCT) of 8 weeks of treatment for cocaine-use disorder and randomized to outpatient treatment as usual (TAU) or computer-based cognitive-behavioral therapy (CBT4CBT) plus TAU. Participants completed fMRI Color-Word Stroop task at beginning-of-treatment (N = 19) and post-treatment (N = 10). Analyses assessed correlat

SUBMITTER: DeVito EE 

PROVIDER: S-EPMC6374034 | biostudies-literature | 2019 Feb

REPOSITORIES: biostudies-literature