Synthesis of a miniaturized [FeFe] hydrogenase model system.

ABSTRACT: The reaction occurring during artificial maturation of [FeFe] hydrogenase has been recreated using molecular systems. The formation of a miniaturized [FeFe] hydrogenase model system, generated through the combination of a [4Fe4S] cluster binding oligopeptide and an organometallic Fe complex, has been monitored by a range of spectroscopic techniques. A structure of the final assembly is suggested based on EPR and FTIR spectroscopy in combination with DFT calculations. The capacity of this novel H-cluster model to catalyze H2 production in aqueous media at mild potentials is verified in chemical assays.

SUBMITTER: Esmieu C 

PROVIDER: S-EPMC6374738 | biostudies-literature | 2019 Feb

REPOSITORIES: biostudies-literature