COMPare: a prospective cohort study correcting and monitoring 58 misreported trials in real time.

ABSTRACT:

Background

Discrepancies between pre-specified and reported outcomes are an important source of bias in trials. Despite legislation, guidelines and public commitments on correct reporting from journals, outcome misreporting continues to be prevalent. We aimed to document the extent of misreporting, establish whether it was possible to publish correction letters on all misreported trials as they were published, and monitor responses from editors and trialists to understand why outcome misreporting persists despite public commitments to address it.

Methods

We identified five high-impact journals endorsing Consolidated Standards of Reporting Trials (CONSORT) (New England Journal of Medicine, The Lancet, Journal of the American Medical Association, British Medical Journal, and A

SUBMITTER: Goldacre B 

PROVIDER: S-EPMC6375128 | biostudies-literature | 2019 Feb

REPOSITORIES: biostudies-literature