Pesticide Use and Incident Hypothyroidism in Pesticide Applicators in the Agricultural Health Study.

ABSTRACT:

Background

Though evidence suggests that some pesticides may have thyroid-disrupting properties, prospective studies of associations between specific pesticides and incident thyroid disease are limited.

Objective

We evaluated associations between use of specific pesticides and incident hypothyroidism in private pesticide applicators in the Agricultural Health Study (AHS).

Methods

Self-reported incident hypothyroidism ([Formula: see text] cases) was studied in relation to ever-use and intensity-weighted cumulative days of pesticide use at study enrollment. We estimated adjusted hazard ratios (HRs) and 95% confidence intervals (CI) using Cox proportional hazards models applied to 35,150 male and female applicators followed over 20 y. All models were stratified by state

SUBMITTER: Shrestha S 

PROVIDER: S-EPMC6375417 | biostudies-literature | 2018 Sep

REPOSITORIES: biostudies-literature