Highly efficient and sensitive patient-specific quality assurance for spot-scanned proton therapy.

ABSTRACT: The purpose of this work was to develop an end-to-end patient-specific quality assurance (QA) technique for spot-scanned proton therapy that is more sensitive and efficient than traditional approaches. The patient-specific methodology relies on independently verifying the accuracy of the delivered proton fluence and the dose calculation in the heterogeneous patient volume. A Monte Carlo dose calculation engine, which was developed in-house, recalculates a planned dose distribution on the patient CT data set to verify the dose distribution represented by the treatment planning system. The plan is then delivered in a pre-treatment setting and logs of spot position and dose monitors, which are integrated into the treatment nozzle, are recorded. A computational routine compares the delivery lo

SUBMITTER: Johnson JE 

PROVIDER: S-EPMC6375645 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature