Body Composition Remodeling and Incident Mobility Limitations in African Ancestry Men.

ABSTRACT:

Background

Mobility limitations are common, with higher prevalence in African Americans compared with whites, and are associated with disability, institutionalization, and death. Aging is associated with losses of lean mass and a shift to central adiposity, which are more pronounced in African Americans. We aimed to examine the association of body composition remodeling with incident mobility limitations in older men of African ancestry.

Methods

Seven-year changes in body composition were measured using peripheral quantitative computed tomography (pQCT) of the calf and whole-body dual x-ray absorptiometry (DXA) in 505 African ancestry men aged ≥60 years and free of self-reported mobility limitations at baseline. Self-reported incident mobility limitations were assessed at 7-

SUBMITTER: Santanasto AJ 

PROVIDER: S-EPMC6376082 | biostudies-literature | 2019 Feb

REPOSITORIES: biostudies-literature