Concentrations of endocrine disrupting chemicals in newborn blood spots and infant outcomes in the upstate KIDS study.

ABSTRACT:

Background

Novel methodologies to quantify infant exposures to endocrine disrupting chemicals (EDCs) for population-based studies are needed.

Objectives

We used newborn dried blood spots to quantify three EDCs and their associations with infant outcomes in the Upstate KIDS Cohort.

Methods

We measured bisphenol A (BPA), perfluorooctanesulfonic acid (PFOS) and perfluorooctanoic acid (PFOA) in 2071 singleton and 1040 twin infants born to mothers in New York State. We log transformed concentrations after rescaling by their standard deviations and modeled each in relation to gestational age, birthweight, length, head circumference and Ponderal Index (PI) using linear regression techniques. All models were adjusted for maternal age, body mass index, education, infertility t

SUBMITTER: Bell EM 

PROVIDER: S-EPMC6376484 | biostudies-literature | 2018 Dec

REPOSITORIES: biostudies-literature