Central Blood Pressure and Pulse Wave Velocity Changes Post Renal Denervation in Patients With Stages 3 and 4 Chronic Kidney Disease: The Regina RDN Study.

ABSTRACT:

Background

Central aortic blood pressures and arterial stiffness are better indicators of cardiovascular outcomes than brachial blood pressures. However, their response to renal denervation (RDN) in patients with Stage 3 and Stage 4 chronic kidney disease (CKD) has not yet been examined.

Objective

To evaluate the impact of RDN on central blood pressures (CBP), brachial (office and ambulatory) blood pressures, arterial stiffness, glomerular filtration rate (GFR), 24-hour urine protein, and selective cardiac parameters observed on echocardiograms.

Design

Single-center, single-arm with pre-/post-RDN follow-up.

Setting

Patients were recruited from the multidisciplinary CKD clinic, Regina General Hospital, Canada.

Patients

About 25 consecutive patients with S

SUBMITTER: Prasad B 

PROVIDER: S-EPMC6376516 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature