Sensory evaluation of edoxaban orally disintegrating tablets: an open-label interventional study (secondary publication).

ABSTRACT:

Background

This study involved a sensory evaluation of edoxaban orally disintegrating (OD) tablets in patients with nonvalvular atrial fibrillation who had been receiving the existing edoxaban film-coated tablets before the study.

Methods

Edoxaban OD tablets 30 or 60 mg were prescribed for patients who had been receiving the existing 30- or 60-mg edoxaban film-coated tablets before the study. Each dose group was randomized into groups taking the tablets with or without water. After ingestion of the edoxaban OD tablet, each patient was asked to complete a sensory evaluation questionnaire (12 items).

Results

In the evaluation of satisfaction with edoxaban OD tablets, 52.8% of the patients perceived "no difference" from the existing edoxaban film-coated tablets and 34.9%

SUBMITTER: Yamashita T 

PROVIDER: S-EPMC6376672 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature