Autoantibody detection is not recommended for chronic pancreatitis: a cross-sectional Study of 557 patients.

ABSTRACT:

Background

Autoimmune factor was regarded as one of the risk factors in the pathogenesis of chronic pancreatitis (CP), especially for autoimmune pancreatitis (AIP). However, whether autoimmune factor plays a role in non-AIP CP or not was unknown.

Methods

Hospitalized patients with non-AIP CP from January 2010 to October 2016 were detected for 22 autoantibodies at the time of hospital admission. Autoantibodies with frequency > 0.5% were enrolled to calculate the frequency in historial healthy controls through literature search in PubMed. Differentially expressed autoantibodies were determined between patients and historial healthy controls, and related factors were identified by multivariate logistic regression analysis.

Results

In a total of 557 patients, 113 cases we

SUBMITTER: Zeng XP 

PROVIDER: S-EPMC6376735 | biostudies-literature | 2019 Feb

REPOSITORIES: biostudies-literature