Identification and co-evolution pattern of stem cell regulator miR394s and their targets among diverse plant species.

ABSTRACT:

Background

Micro RNAs (miRNAs), a class of small non-coding RNAs, have been implicated in various aspects of plant development. miR394 is required for shoot apical meristem organization, stem cell maintenance and abiotic stress responses in Arabidopsis, where it functions by negatively regulating the transcript level of target LEAF CURLING RESPONSIVENESS (LCR), which is an F-box protein-coding gene. The evolutionary conservation of stem cell regulatory miR394-LCR module among plants remains elusive.

Results

Our study has identified 79 miR394 and 43 target sequences across 40 plant species using various homology based search tools and databases, and analysed their co-evolution pattern. We customised an annotation workflow which computationally validates 20 novel miR394s from

SUBMITTER: Kumar A 

PROVIDER: S-EPMC6376759 | biostudies-literature | 2019 Feb

REPOSITORIES: biostudies-literature