Frailty and Clinical Outcomes in Chronic Obstructive Pulmonary Disease.

ABSTRACT:

Rationale

Frailty represents an increased vulnerability to adverse health outcomes. The frailty phenotype conceptual model (three or more patient attributes of wasting, exhaustion, low activity, slowness, and weakness) is associated with increased morbidity and mortality in geriatric populations.

Objectives

Our objective was to describe the risks associated with frailty in patients with chronic obstructive pulmonary disease.

Methods

Data from the National Emphysema Treatment Trial (NETT) were retrospectively analyzed. The frailty phenotype conceptual model was operationalized as three or more frailty parameters (a body mass index decrease of ≥5% over 12 months, self-reported exhaustion, low 6-minute walk distance, or physical activity or respiratory muscle strength in

SUBMITTER: Kennedy CC 

PROVIDER: S-EPMC6376949 | biostudies-literature | 2019 Feb

REPOSITORIES: biostudies-literature