A unified statistical model for the human electrocorticogram.

ABSTRACT:

Objective

Extracellular field potentials (ECFs) generated in the cerebral cortex span a vast range of spatiotemporal scales. The process(es) leading to this large dynamic range remain debatable. Here we propose a novel statistical description of the amplitude spectrum of the human electrocorticogram (ECoG).

Methods

Spectral analysis was performed on long-term recordings from epilepsy patients undergoing pre-surgical evaluation with intracranial electrodes. Amplitude spectra were fit with a multi-component Gaussian model on semi-logarithmic axes.

Results

The Gaussian formulation provided excellent fits to the data. It also suggested how the changes accompanying the sleep-wake cycle and certain epileptiform transitions could be understood by variation in the parameters

SUBMITTER: Kalamangalam GP 

PROVIDER: S-EPMC6377706 | biostudies-literature | 2016 Dec

REPOSITORIES: biostudies-literature