A hybrid expert approach for retrospective assessment of occupational exposures in a population-based case-control study of cancer.

ABSTRACT:

Background

While the expert-based occupational exposure assessment approach has been considered the reference method for retrospective population-based studies, its implementation in large study samples has become prohibitive. To facilitate its application and improve upon it we developed, in the context of a Montreal population-based study of prostate cancer (PROtEuS), a hybrid approach combining job-exposure profiles (JEPs) summarizing expert evaluations from previous studies and expert review. We aim to describe the hybrid expert method and its impacts on the exposures assigned in PROtEuS compared to those from a previous study coded using the traditional expert method.

Methods

Applying the hybrid approach, experts evaluated semi-quantitative levels of confidence, concent

SUBMITTER: Sauve JF 

PROVIDER: S-EPMC6377721 | biostudies-literature | 2019 Feb

REPOSITORIES: biostudies-literature