Functional Heatmap: an automated and interactive pattern recognition tool to integrate time with multi-omics assays.

ABSTRACT:

Background

Life science research is moving quickly towards large-scale experimental designs that are comprised of multiple tissues, time points, and samples. Omic time-series experiments offer answers to three big questions: what collective patterns do most analytes follow, which analytes follow an identical pattern or synchronize across multiple cohorts, and how do biological functions evolve over time. Existing tools fall short of robustly answering and visualizing all three questions in a unified interface.

Results

Functional Heatmap offers time-series data visualization through a Master Panel page, and Combined page to answer each of the three time-series questions. It dissects the complex multi-omics time-series readouts into patterned clusters with associated biologica

SUBMITTER: Williams JR 

PROVIDER: S-EPMC6377781 | biostudies-literature | 2019 Feb

REPOSITORIES: biostudies-literature