Metabolite Markers for Characterizing Sasang Constitution Type through GC-MS and ¹H NMR-Based Metabolomics Study.

ABSTRACT: Sasang constitutional medicine classifies human beings into four types based on their physical and psychological characteristics. Despite its potential value in achieving personalized medicine, the diagnosis of sasang constitution (SC) type is complex and subjective. In this study, gas chromatography-mass spectrometry and ¹H nuclear magnetic resonance-based metabolic analyses were conducted to find maker metabolites in serum and urine according to different SC types. Although some samples were overlapped on orthogonal projection to latent structure discriminant analysis score plots, serum samples showed separation between different SC types. Levels of lactate, glutamate, triglyceride, and fatty acids in serum and glycolic acid in urine of Tae-Eum type were higher than those of S

SUBMITTER: Kim EJ 

PROVIDER: S-EPMC6378031 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature