Group B Streptococcus (GBS) Colonization and Disease among Pregnant Women: A Historical Cohort Study.

ABSTRACT:

Background

Maternal GBS colonization is associated with early-onset neonatal sepsis and extensive efforts are directed to preventing this complication. Less is known about maternal risks of GBS colonization. We seek to provide a modern estimate of the incidence and impact of maternal GBS colonization and invasive GBS disease.

Methods

A single center historical cohort study of all births between 2003 and 2015 was performed. Data was collected via electronic health record abstraction using an institutional specific tool. Descriptive statistics were performed regarding GBS status. Inferential statistics were performed comparing risk of adverse pregnancy outcomes in cohorts with and without GBS colonization as well as cohorts with GBS colonization and invasive GBS disease.

Re

SUBMITTER: Edwards JM 

PROVIDER: S-EPMC6378061 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature