Cost-effectiveness of surveillance schedules in older adults with non-muscle-invasive bladder cancer.

ABSTRACT:

Objective

To estimate the cost-effectiveness of surveillance schedules for non-muscle-invasive bladder cancer (NMIBC) amongst older adults.

Patients and methods

We developed a MIcrosimulation SCreening ANalysis (MISCAN) microsimulation model to compare the cost-effectiveness of various surveillance schedules (every 3 months to every 24 months, for 2, 5 or 10 years or lifetime) for older adults (aged 65-85 years) with NMIBC. For each surveillance schedule we calculated total costs per patient and the number of quality adjusted life-years (QALYs) gained. Incremental cost-effectiveness ratios (ICERs), as incremental costs per QALY gained, were calculated using a 3% discount.

Results

As age increased, the number of QALYs gained per patient decreased substantially. Surveil

SUBMITTER: Heijnsdijk EAM 

PROVIDER: S-EPMC6378589 | biostudies-literature | 2019 Feb

REPOSITORIES: biostudies-literature