Effectiveness of different accelerated partial breast irradiation techniques for the treatment of breast cancer patients: Systematic review using indirect comparisons of randomized clinical trials.

ABSTRACT:

Aim

This systematic review was conducted to compare the effectiveness of different accelerated partial breast irradiation (APBI) techniques for the treatment of breast cancer patients.

Background

Numerous (APBI) techniques are available for clinical practice.

Methods and materials

Systematic review of randomized controlled trials of APBI versus whole breast irradiation (WBI). The data from APBI studies were extracted for the analyses. Indirect comparisons were used to compare different APBI techniques.

Results

Ten studies fulfilled the inclusion criteria. A total of 4343 patients were included, most of them with tumor stage T1-T2 and N0. Regarding APBI techniques, six trials used external beam radiation therapy; one intraoperative electrons; one intraoperative

SUBMITTER: Marta GN 

PROVIDER: S-EPMC6378667 | biostudies-literature | 2019 Mar-Apr

REPOSITORIES: biostudies-literature