High Pesticide Exposure Events and Olfactory Impairment among U.S. Farmers.

ABSTRACT:

Background

Olfactory impairment (OI) is common among older adults and independently predicts all-cause mortality and the risk of several major neurodegenerative diseases. Pesticide exposure may impair olfaction, but empirical evidence is lacking.

Objective

We aimed to examine high pesticide exposure events (HPEEs) in relation to self-reported OI in participants in the Agricultural Health Study (AHS).

Methods

We conducted multivariable logistic regression to examine the associations between HPEEs reported at enrollment (1993–1997) and self-reported OI at the latest AHS follow-up (2013–2015) among 11,232 farmers, using farmers without HPEEs as the reference or unexposed group.

Results

A total of 1,186 (10.6%) farmers reported OI. A history of HPEEs reported at en

SUBMITTER: Shrestha S 

PROVIDER: S-EPMC6378679 | biostudies-literature | 2019 Jan

REPOSITORIES: biostudies-literature