Cerebral infarction after fractionated stereotactic radiation therapy of benign anterior skull base tumors.

ABSTRACT:

Background

The purpose of this study was to examine the occurrence of cerebral infarction (ischemic stroke), in a large combined cohort of patients with anterior skull base meningiomas, pituitary adenomas and craniopharyngiomas, after fractionated stereotactic radiation therapy (FSRT).

Material and methods

All patients, 18 years and older, with anterior skull base meningiomas, pituitary adenomas and craniopharyngiomas, treated with fractionated stereotactic radiation, in our center, from January 1999 to December 2015 were identified. In total 169 patients were included. The prescription dose to the tumor was 54 Gy for 164 patients (97%) and 46.0-52.2 Gy for 5 patients (3%). Cases of cerebral infarctions subsequent to FSRT were identified from the Danish National Patient Regi

SUBMITTER: Astradsson A 

PROVIDER: S-EPMC6378839 | biostudies-literature | 2019 Feb

REPOSITORIES: biostudies-literature