Development and validation of the pediatric risk estimate score for children using extracorporeal respiratory support (Ped-RESCUERS).

ABSTRACT:

Purpose

To develop and validate the Pediatric Risk Estimation Score for Children Using Extracorporeal Respiratory Support (Ped-RESCUERS). Ped-RESCUERS is designed to estimate the in-hospital mortality risk for children prior to receiving respiratory extracorporeal membrane oxygenation (ECMO) support.

Methods

This study used data from an international registry of patients aged 29 days to less than 18 years who received ECMO support from 2009 to 2014. We divided the registry into development and validation datasets by calendar date. Candidate variables were selected for model inclusion if the variable independently changed the mortality risk by at least 2 % in a Bayesian logistic regression model with in-hospital mortality as the outcome. We characterized the model's ability t

SUBMITTER: Barbaro RP 

PROVIDER: S-EPMC6379065 | biostudies-literature | 2016 May

REPOSITORIES: biostudies-literature