Background field removal for susceptibility mapping of human brain with large susceptibility variations.

ABSTRACT:

Purpose

In quantitative susceptibility mapping (QSM) of human brain, the background field induced by air-tissue interface varies significantly with respect to the rotation angle between the head and the static field, which may result in substantial error in the estimated magnetic susceptibility values. The goal of this study was to develop a strategy to better remove such orientation dependent background field.

Methods

An improved background field removal method is proposed based on the sophisticated harmonic artifact reduction for phase data using a region adaptive kernel (R-SHARP), named iRSHARP. It uses a spatially weighted spherical Gaussian kernel exploiting the amplitude, gradient, and wrap count of the phase map. The method was validated using both numerical simulatio

SUBMITTER: Fang J 

PROVIDER: S-EPMC6379075 | biostudies-literature | 2019 Mar

REPOSITORIES: biostudies-literature