Comparative analysis of seven types of superoxide dismutases for their ability to respond to oxidative stress in Bombyx mori.

ABSTRACT: Insects are well adapted to changing environmental conditions. They have unique systems for eliminating reactive oxygen species (ROS). Superoxide dismutase (SOD) is a key enzyme that plays a primary role in removing ROS. Bombyx mori is a lepidopteran insect, whose body size is larger than the model insect Drosophila melanogaster, which enabled us to more easily examine gene expression at the tissue level. We searched B. mori SOD (BmSOD) genes using genome database, and we analyzed their function under different type of oxidative stress. Consequently, we identified four new types of BmSODs in addition to the three types already known. Two of the seven types had a unique domain architecture that has not been discovered previously in the SOD family, and they were expressed in different tissue

SUBMITTER: Kobayashi Y 

PROVIDER: S-EPMC6379424 | biostudies-literature | 2019 Feb

REPOSITORIES: biostudies-literature