Mucinous Cystadenoma in Children and Adolescents.

ABSTRACT:

Study objective

Mucinous cystadenomas (MCAs) are benign epithelial ovarian tumors that occur rarely in children and adolescents. Because children and adolescents typically have their childbearing years ahead of them, conservative therapy is indicated. However, there is concern that ovarian cystectomy might be associated with significant recurrence risk in patients with MCA. Furthermore, guanine nucleotide binding protein, alpha stimulating (GNAS) gene mutations are associated with McCune-Albright syndrome, which is associated with cystic ovaries. We sought to evaluate the outcomes of children and adolescents with MCA treated conservatively. A subset of patients underwent GNAS gene testing.

Design, setting, participants, and interventions

After institutional board review appr

SUBMITTER: Cowan RA 

PROVIDER: S-EPMC6379898 | biostudies-literature | 2017 Aug

REPOSITORIES: biostudies-literature