Invasive and non-invasive diagnostic approaches for microbiological diagnosis of hospital-acquired pneumonia.

ABSTRACT:

Background

Data on the methods used for microbiological diagnosis of hospital-acquired pneumonia (HAP) are mainly extrapolated from ventilator-associated pneumonia. HAP poses additional challenges for respiratory sampling, and the utility of sputum or distal sampling in HAP has not been comprehensively evaluated, particularly in HAP admitted to the ICU.

Methods

We analyzed 200 patients with HAP from six ICUs in a teaching hospital in Barcelona, Spain. The respiratory sampling methods used were divided into non-invasive [sputum and endotracheal aspirate (EAT)] and invasive [fiberoptic-bronchoscopy aspirate (FBAS), and bronchoalveolar lavage (BAL)].

Results

A median of three diagnostic methods were applied [range 2-4]. At least one respiratory sampling method was applie

SUBMITTER: Ranzani OT 

PROVIDER: S-EPMC6379979 | biostudies-literature | 2019 Feb

REPOSITORIES: biostudies-literature