Red blood cell transfusion in acute brain injury subtypes: An observational cohort study.

ABSTRACT:

Purpose

Optimal red blood cell (RBC) transfusion thresholds in acute brain injury (ABI) are poorly defined.

Materials and methods

We conducted a retrospective cohort study of adult patients with ABI and moderate anemia (Hb 7-10 g/dL) in a neurological intensive care unit (ICU) at an academic medical center between 2008 and 2015. Transfused and non-transfused patients were matched based on age, ABI subtype, pre-transfusion hemoglobin, and ICU length of stay (LOS) at the time of RBC transfusion. Multivariable regression analyses were performed to assess the relationship between RBC transfusion and hospital LOS, hospital mortality, ICU LOS, ICU mortality, and 24 h change in sequential organ failure assessment (SOFA) scores.

Results

2638 patients met inclusion criteria, w

SUBMITTER: Moman RN 

PROVIDER: S-EPMC6381596 | biostudies-literature | 2019 Apr

REPOSITORIES: biostudies-literature