Molecular epidemiology of an enterovirus A71 outbreak associated with severe neurological disease, Spain, 2016.

ABSTRACT: IntroductionEnterovirus A71 (EV-A71) is an emerging pathogen that causes a wide range of disorders including severe neurological manifestations. In the past 20 years, this virus has been associated with large outbreaks of hand, foot and mouth disease with neurological complications in the Asia-Pacific region, while in Europe mainly sporadic cases have been reported. In spring 2016, however, an EV-A71 outbreak associated with severe neurological cases was reported in Catalonia and spread further to other Spanish regions.AimOur objective was to investigate the epidemiology and clinical characteristics of the outbreak.MethodsWe carried out a retrospective study which included 233 EV-A71-positive samples collected during 2016 from hospitalised patients. We analysed the clinical manifestations

SUBMITTER: Gonzalez-Sanz R 

PROVIDER: S-EPMC6381658 | biostudies-literature | 2019 Feb

REPOSITORIES: biostudies-literature