Metal exposure and oxidative stress markers in pregnant Navajo Birth Cohort Study participants.

ABSTRACT: Contamination of soil and water by waste from abandoned uranium mines has led to chronic exposures to metal mixtures in Native American communities. Our previous work demonstrated that community exposures to mine waste increase the likelihood of developing cardiovascular disease, as well as the likelihood of developing multiple chronic diseases including diabetes, hypertension and kidney disease. Exposure to various environmental metals is associated with elevated oxidative stress, which is considered a contributor to these and other chronic disease states. The purpose of the current research was to assess potential associations between exposure to uranium and arsenic and evidence for increased oxidative stress as measured by urinary F₂ -isoprostanes in pregnant women enrolled i

SUBMITTER: Dashner-Titus EJ 

PROVIDER: S-EPMC6381929 | biostudies-literature | 2018 Aug

REPOSITORIES: biostudies-literature