Macula Vessel Density and Thickness in Early Primary Open-Angle Glaucoma.

ABSTRACT:

Purpose

To characterize and compare the ganglion cell complex (GCC) thickness and macula vessel density in preperimetric and early primary open-angle glaucoma (POAG) eyes.

Design

Cross-sectional study.

Methods

Fifty-seven healthy, 68 preperimetric, and 162 early POAG eyes enrolled in the Diagnostic Innovations in Glaucoma Study. Optical coherence tomography angiography (OCT-A)-based superficial macula vessel density and OCT-based GCC thickness were evaluated simultaneously. Percent loss from normal of GCC thickness and macula vessel density was compared. Area under the receiver operating characteristic curve was used to describe the diagnostic utility.

Results

Both GCC thickness and vessel density were significantly lower in preperimetric and early POAG eyes co

SUBMITTER: Hou H 

PROVIDER: S-EPMC6382614 | biostudies-literature | 2019 Mar

REPOSITORIES: biostudies-literature