Modeling the impact of quarantine during an outbreak of Ebola virus disease.

ABSTRACT: The quarantine of people suspected of being exposed to an infectious agent is one of the most basic public health measure that has historically been used to combat the spread of communicable diseases in human communities. This study presents a new deterministic model for assessing the population-level impact of the quarantine of individuals suspected of being exposed to disease on the spread of the 2014-2015 outbreaks of Ebola viral disease. It is assumed that quarantine is imperfect (i.e., individuals can acquire infection during quarantine). In the absence of quarantine, the model is shown to exhibit global dynamics with respect to the disease-free and its unique endemic equilibrium when a certain epidemiological threshold (denoted by R0 ) is either less than or greater than unity. Thus,

SUBMITTER: Denes A 

PROVIDER: S-EPMC6382747 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature