Sex differences in the ¹H NMR metabolic profile of serum in cardiovascular risk patients.

ABSTRACT: Personalized diagnosis and risk stratification of cardiovascular diseases would allow optimizing therapeutic strategies and lifestyle changes. Metabolomics is a promising technique for personalized diagnosis and prognosis; however, various physiological parameters, including sex, influence the metabolic profile thus hampering its translation to the clinic. Knowledge of the variation in the metabolic profile associated with sex would facilitate metabolomic translation to the clinic. The objective of the present work was to investigate the possible differences in the metabolic ¹H NMR profile associated to sex beyond lipoproteins. ¹H NMR spectra from whole serum and methanol deproteinized samples from 39 patients (22 males, 17 females) between 55-70 years old with suspec

SUBMITTER: Barba I 

PROVIDER: S-EPMC6382944 | biostudies-literature | 2019 Feb

REPOSITORIES: biostudies-literature