HBV vaccination and PMTCT as elimination tools in the presence of HIV: insights from a clinical cohort and dynamic model.

ABSTRACT:

Background

Sustainable Development Goals set a challenge for the elimination of hepatitis B virus (HBV) infection as a public health concern by the year 2030. Deployment of a robust prophylactic vaccine and enhanced interventions for prevention of mother to child transmission (PMTCT) are cornerstones of elimination strategy. However, in light of the estimated global burden of 290 million cases, enhanced efforts are required to underpin optimisation of public health strategy. Robust analysis of population epidemiology is particularly crucial for populations in Africa made vulnerable by HIV co-infection, poverty, stigma and poor access to prevention, diagnosis and treatment.

Methods

We here set out to evaluate the current and future role of HBV vaccination and PMTCT as tools f

SUBMITTER: McNaughton AL 

PROVIDER: S-EPMC6383254 | biostudies-literature | 2019 Feb

REPOSITORIES: biostudies-literature