Wearable Cardioverter-Defibrillator Therapy for the Prevention of Sudden Cardiac Death: A Systematic Review and Meta-Analysis.

ABSTRACT:

Objectives

This study sought to synthesize the available evidence on the use of the wearable cardioverter-defibrillator (WCD).

Background

Observational WCD studies for the prevention of sudden cardiac death have provided conflicting data. The VEST (Vest Prevention of Early Sudden Death) trial was the first randomized controlled trial (RCT) showing no reduction in sudden cardiac death as compared to medical therapy only.

Methods

We searched PubMed, EMBASE, and Google Scholar for studies reporting on the outcomes of patients wearing WCDs from January 1, 2001, through March 20, 2018. Rates of appropriate and inappropriate WCD therapies were pooled. Estimates were derived using DerSimonian and Laird's method.

Results

Twenty-eight studies were included (N = 33,242;

SUBMITTER: Masri A 

PROVIDER: S-EPMC6383782 | biostudies-literature | 2019 Feb

REPOSITORIES: biostudies-literature