Transcatheter, sutureless and conventional aortic-valve replacement: a network meta-analysis of 16,432 patients.

ABSTRACT:

Background

Minimally invasive surgical techniques pose alternatives to conventional surgery for the treatment of aortic stenosis (AS). We present a Bayesian network analysis comparing Valve Academic Research Consortium-2 clinical outcomes between transcatheter aortic valve implantation (TAVI), sutureless (SL-AVR) and conventional aortic valve replacement (CAVR).

Methods

Electronic searches of databases were conducted and seven two-arm randomized-controlled trials and 25 propensity-score-matched studies comparing clinical outcomes of TAVI, SL-AVR and CAVR for treatment of AS were identified. Bayesian Markov chain Monte Carlo modelling was used to analyze clinical outcomes.

Results

The analysis included 16,432 patients who underwent TAVI [7,056], SL-AVR [1,238] or CAVR

SUBMITTER: Lloyd D 

PROVIDER: S-EPMC6384334 | biostudies-literature | 2019 Jan

REPOSITORIES: biostudies-literature