Ontology highlight
ABSTRACT:
SUBMITTER: Wang J
PROVIDER: S-EPMC6384703 | biostudies-literature | 2019 Jan
REPOSITORIES: biostudies-literature
Molecules (Basel, Switzerland) 20190128 3
<i>Streptococcus mutans</i> (<i>S. mutans</i>) is the primary etiological agent of dental caries. The <i>S. mutans</i> enzyme sortase A (SrtA) is responsible for anchoring bacterial cell wall surface proteins involved in host cell attachment and biofilm formation. Thus, SrtA is an attractive target for inhibiting dental caries caused by <i>S. mutans</i>-associated acid fermentation. In this study, we observed that astilbin, a flavanone compound extracted from <i>Rhizoma Smilacis Glabrae</i>, has ...[more]