BF₃-Promoted, Carbene-like, C-H Insertion Reactions of Benzynes.

ABSTRACT: Boron trifluoride is observed to promote a variety of C-H insertion reactions of benzynes bearing pendant alkyl groups. Computations and various mechanistic studies indicate that BF₃ engages the strained π-bond to confer carbene-like character on the adjacent, noncoordinated benzyne carbon. This represents an unprecedented catalytic role for a non-transition metal such as BF₃.

SUBMITTER: Shen H 

PROVIDER: S-EPMC6386166 | biostudies-literature | 2018 Nov

REPOSITORIES: biostudies-literature