Choriocapillaris flow impairment surrounding geographic atrophy correlates with disease progression.

ABSTRACT:

Purpose

To evaluate the correlation between the choriocapillaris (CC) flow alterations around geographic atrophy (GA) and the GA yearly growth rate (yGR) in patients with dry age-related macular degeneration (AMD).

Methods

We retrospectively reviewed and analyzed spectral domain optical coherence tomography (SD-OCT) and SD-OCT angiography images of consecutive patients with GA acquired using the Cirrus OCT at the Doheny Eye Centers between 2015 and 2017. All eligible patients had one 6 x 6 mm OCTA scan acquired during the first visit (considered as baseline) and two fovea-centered 512 x 128 macular cubes (6 x 6 mm) acquired at baseline and after a minimum of 12 months.

Main outcome measures

The fundus images from the OCT volumes were used to manually delineate the GA

SUBMITTER: Nassisi M 

PROVIDER: S-EPMC6386298 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature