Environmental safety during the administration of Pressurized IntraPeritoneal Aerosol Chemotherapy (PIPAC).

ABSTRACT:

Background

Pressurized IntraPeritoneal Aerosol Chemotherapy (PIPAC) is an innovative technique for intraperitoneal drug delivery. This study investigates the efficacy of the occupational health safety measures taken to prevent exposition of healthcare workers to the toxic chemotherapy aerosol.

Methods

Air samples were taken at the working place of the surgeon and of the anesthetist during 2 PIPAC procedures and analyzed for content of platinum by inductively coupled plasma mass spectrometry (ICP-MS). Airborne particles were quantified in real time. Biological monitoring was performed in two surgeons after 50 PIPAC by examining blood samples for possible traces of platinum. Analysis was performed by an independent company.

Results

Safety measures included tightly close

SUBMITTER: Graversen M 

PROVIDER: S-EPMC6386395 | biostudies-literature | 2016 Dec

REPOSITORIES: biostudies-literature