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Spatial soft sweeps: Patterns of adaptation in populations with long-range dispersal.


ABSTRACT: Adaptation in extended populations often occurs through multiple independent mutations responding in parallel to a common selection pressure. As the mutations spread concurrently through the population, they leave behind characteristic patterns of polymorphism near selected loci-so-called soft sweeps-which remain visible after adaptation is complete. These patterns are well-understood in two limits of the spreading dynamics of beneficial mutations: the panmictic case with complete absence of spatial structure, and spreading via short-ranged or diffusive dispersal events, which tessellates space into distinct compact regions each descended from a unique mutation. However, spreading behaviour in most natural populations is not exclusively panmictic or diffusive, but incorporates both short-r

SUBMITTER: Paulose J 

PROVIDER: S-EPMC6386408 | biostudies-literature | 2019 Feb

REPOSITORIES: biostudies-literature