Disparity in access to kidney allograft offers among transplant candidates with human immunodeficiency virus.

ABSTRACT:

Background

Despite a survival benefit from transplantation and acceptable outcomes, patients with human immunodeficiency virus (HIV+) face barriers to kidney transplantation. Little is known about the acceptance or decline of organ offers on their behalf because waitlist registry data do not include HIV serostatus.

Methods

We performed a retrospective cohort study using match run data from the Organ Procurement and Transplantation Network, including every kidney offer from May 1, 2007, to July 3, 2013. HIV and hepatitis C virus (HCV) serostatus were obtained by merging the match run with clinical data from a large dialysis provider. We used Cox proportional hazards modeling to evaluate differences in time to the first organ offer and to transplantation. A total of 35 646 uni

SUBMITTER: Cohen JB 

PROVIDER: S-EPMC6386602 | biostudies-literature | 2019 Feb

REPOSITORIES: biostudies-literature