Occupational Exposures and Neurodegenerative Diseases-A Systematic Literature Review and Meta-Analyses.

ABSTRACT: Objectives: To carry out an integrated and stratified meta-analysis on occupational exposure to electromagnetic fields (EMFs), metals and pesticides and its effects on amyotrophic lateral sclerosis (ALS) and Parkinson's and Alzheimer's disease, and investigate the possibility of publication bias. Methods: In the current study, we updated our recently published meta-analyses on occupational exposures in relation to ALS, Alzheimer's and Parkinson's disease. Based on 66 original publications of good scientific epidemiological standard, according to the Meta-analysis of Observational Studies in Epidemiology (MOOSE) and the Grading of Recommendations, Assessment, Development and Evaluations (GRADE) guidelines, we analysed subgroups by carrying out stratified meta-analyses on publication year, s

SUBMITTER: Gunnarsson LG 

PROVIDER: S-EPMC6388365 | biostudies-literature | 2019 Jan

REPOSITORIES: biostudies-literature