A simple decontamination approach using hydrogen peroxide vapour for Bacillus anthracis spore inactivation.

ABSTRACT:

Aims

To evaluate the use of relatively low levels of hydrogen peroxide vapour (HPV) for the inactivation of Bacillus anthracis spores within an indoor environment.

Methods and results

Laboratory-scale decontamination tests were conducted using bacterial spores of both B. anthracis Ames and Bacillus atrophaeus inoculated onto several types of materials. Pilot-scale tests were also conducted using a larger chamber furnished as an indoor office. Commercial off-the-shelf (COTS) humidifiers filled with aqueous solutions of 3 or 8% hydrogen peroxide (H₂ O₂ ) were used to generate the HPV inside the mock office. The spores were exposed to HPV for periods ranging from 8 h up to 1 week.

Conclusions

Four- to seven-day exposures to low levels of HPV (averag

SUBMITTER: Wood JP 

PROVIDER: S-EPMC6388395 | biostudies-literature | 2016 Dec

REPOSITORIES: biostudies-literature