A low-cost bioprosthetic semilunar valve for research, disease modelling and surgical training applications.

ABSTRACT:

Objectives

This paper provides detailed instructions for constructing low-cost bioprosthetic semilunar valves for animal research and clinical training. This work fills an important gap between existing simulator training valves and clinical valves by providing fully functioning designs that can be employed in ex vivo and in vivo experiments and can also be modified to model valvular disease.

Methods

Valves are constructed in 4 steps consisting of creating a metal frame, covering it with fabric and attaching a suture ring and leaflets. Computer-aided design files are provided for making the frame from wire or by metal 3D printing. The covering fabric and suturing ring are made from materials readily available in a surgical lab, while the leaflets are made from pericardium. T

SUBMITTER: Rosa B 

PROVIDER: S-EPMC6388656 | biostudies-literature | 2017 Nov

REPOSITORIES: biostudies-literature