The effect of CBT and its modifications for relapse prevention in major depressive disorder: a systematic review and meta-analysis.

ABSTRACT:

Background

The risk of relapse in major depressive disorder (MDD) is associated with high worldwide disease burden. Cognitive behavioral therapy (CBT) and its modifications might be effective in relapse prevention. The aim of this review was to evaluate the efficacy of these treatments for reducing relapse of MDD.

Methods

The retrieval was performed in the databases of MEDLINE via Pubmed, EMBASE and PsycINFO via OVID, The Cochrane Library and four Chinese databases. Clinical trials registry platforms and references of relevant articles were retrieved as well. Hazard ratio (HR) and corresponding 95% confidence interval (CI) were used to pool evidences.

Results

A total of 16 eligible trials involving 1945 participants were included. In the first 12 months, CBT was more

SUBMITTER: Zhang Z 

PROVIDER: S-EPMC6389220 | biostudies-literature | 2018 Feb

REPOSITORIES: biostudies-literature